Detail publikace

Antimicrobials for future infection control and treatment: What clinicians need and what biotechnicians have

LIPOVÝ, B. RAŠKA, F. HOLOUBEK, J. KNOZ, M. HLADÍK, M. KEMPNÝ, T. JANDA, L. KOBZOVÁ, Š. VACEK, L. RŮŽIČKA, F. VOJTOVÁ, L.

Originální název

Typ

abstrakt

Jazyk

angličtina

Originální abstrakt

Infectious complications caused by Staphylococcus aureus (SA) strains represent a significant burden for worldwide healthcare systems from an epidemiological, economic and health point of view. Despite the dedication of considerable financial, research and clinical resources, infections with this pathogen are burdened with unsatisfactory results. The progression in the selection of resistant forms of strains (methicillin-resistant SA - MRSA, glycopeptide-intermediate-resistant SA - GISA, vancomycin-resistant SA - VRSA, linezolid-resistant-MRSA, etc.) very often causes a dramatic reduction in the therapeutic possibilities with classic antimicrobials. Other assumptions are not very favorable, and therefore the search for new possibilities or a return to previously established therapeutic concepts with the use of novel biotechnological processing is essential. The resentation is focused on the current strategies for solving soft tissue and hard tissue infectious complications caused by SA and the current outlook on possible therapeutic alternatives using innovative options, such as phage therapy, enzybiotics, and antimicrobial peptides.

Klíčová slova

infection, resistant strains, pathogen, soft tissue, hard tissue, antimicrobial

Autoři

LIPOVÝ, B.; RAŠKA, F.; HOLOUBEK, J.; KNOZ, M.; HLADÍK, M.; KEMPNÝ, T.; JANDA, L.; KOBZOVÁ, Š.; VACEK, L.; RŮŽIČKA, F.; VOJTOVÁ, L.

Vydáno

21. 8. 2022

Místo

Iceland

Strany od

Strany do

Strany počet

BibTex

@misc{BUT179245,
  author="Břetislav {Lipový} and Filip {Raška} and Jakub {Holoubek} and Martin {Knoz} and Martin {Hladík} and Tomáš {Kempný} and Lubomír {Janda} and Šárka {Kobzová} and Lukáš {Vacek} and Filip {Růžička} and Lucy {Vojtová}",
  title="Antimicrobials for future infection control and treatment: What clinicians need and what biotechnicians have",
  booktitle="International Workshop on Bone and Soft tissues engineering: Structure, chemistry, biomechanics and biology",
  year="2022",
  pages="14--14",
  address="Iceland",
  note="abstract"
}