Detail publikace

Silver nanoparticles stabilised with cationic single-chain surfactants. Structure-physical properties-biological activity relationship study

PISÁRČIK, M. LUKÁČ, M. JAMPÍLEK, J. BILKA, F. BILKOVÁ, A. PAŠKOVÁ, L. DEVÍNSKY, F. HORÁKOVÁ, R. OPRAVIL, T.

Originální název

Silver nanoparticles stabilised with cationic single-chain surfactants. Structure-physical properties-biological activity relationship study

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Increasing number of biological applications of silver nanoparticles requires a detailed determination of the relationship between nanoparticle structure and its physical and biological properties. In this paper, synthesis, measurements of nanoparticle size and zeta potential and some biological activities of silver nanoparticles stabilised with single-chain cationic surfactants are provided. The main goal of the study is the investigation of the relationship between molecular structure of stabilising agent, physicochemical properties and biological activity of cationic surfactant-stabilised silver nanoparticles. Two structural features, heterocyclic character of hydrophilic part of surfactant molecule and hydrophobicity change of its substituents, were correlated with synthesis, stability and biological activity of silver nanoparticles. Substituted ammonium, pyridinium and piperidinium surfactants were selected as stabilisers of silver nanoparticles. It was found that nanoparticle stabilising effect is improved by increasing the length of hydrophobic substituents on the ammonium polar head which results in the formation of nanoparticles small in size and with sufficiently positive zeta potential. Application of dibutylsubstituted ammonium surfactant molecules resulted in the formation of small silver nanoparticles in the size range 25-30 nm and a zeta potential of +60 mV. Aromatic pyridinium surfactant molecules provide slightly better stabilisation than saturated piperidinium surfactants. Surfactant-stabilised silver nanoparticles were antimicrobially efficient against Gram-positive pathogens and yeast. The highest cytotoxic activity was determined for silver nanoparticles stabilised with dibutyl-substituted ammonium surfactant and pyridinium surfactant which corresponds with small and charged nanoparticles formed by using these surfactants. Maximum cytotoxic activity was found in the surfactant concentration range 16-25 mu M. (C) 2018 Published by Elsevier B.V.

Klíčová slova

Silver nanopartide; Ammonium surfactants; Zeta potential; Nanoparticle size

Autoři

PISÁRČIK, M.; LUKÁČ, M.; JAMPÍLEK, J.; BILKA, F.; BILKOVÁ, A.; PAŠKOVÁ, L.; DEVÍNSKY, F.; HORÁKOVÁ, R.; OPRAVIL, T.

Vydáno

15. 12. 2018

Nakladatel

ELSEVIER

Místo

AMSTERDAM

ISSN

0167-7322

Periodikum

JOURNAL OF MOLECULAR LIQUIDS

Ročník

272

Číslo

1

Stát

Nizozemsko

Strany od

60

Strany do

72

Strany počet

13

URL

https://www.webofscience.com/wos/woscc/full-record/WOS:000451494700008

BibTex

@article{BUT177292,
  author="Martin {Pisárčik} and Miloš {Lukáč} and Josef {Jampílek} and František {Bilka} and Andrea {Bilková} and Ludmila {Pašková} and Ferdinand {Devínsky} and Renáta {Horáková} and Tomáš {Opravil}",
  title="Silver nanoparticles stabilised with cationic single-chain surfactants. Structure-physical properties-biological activity relationship study",
  journal="JOURNAL OF MOLECULAR LIQUIDS",
  year="2018",
  volume="272",
  number="1",
  pages="60--72",
  doi="10.1016/j.molliq.2018.09.042",
  issn="0167-7322",
  url="https://www.webofscience.com/wos/woscc/full-record/WOS:000451494700008"
}