Detail publikace

Lumbar Interbody Fusion Conducted on a Porcine Model with a Bioresorbable Ceramic/Biopolymer Hybrid Implant Enriched with Hyperstable Fibroblast Growth Factor 2

KRTIČKA, M. PLÁNKA, L. VOJTOVÁ, L. NEKUDA, V. ŠŤASTNÝ, P. SEDLÁČEK, R. BŘÍNEK, A. KAVKOVÁ, M. GÖPFERT, E. HEDVIČÁKOVÁ, V. RAMPICHOVÁ, M. KŘEN, L. LIŠKOVÁ, K. IRA, D. DORAZILOVÁ, J. SUCHÝ, T. ZIKMUND, T. KAISER, J. STARÝ, D. FALDYNA, M. TRUNEC, M.

Originální název

Lumbar Interbody Fusion Conducted on a Porcine Model with a Bioresorbable Ceramic/Biopolymer Hybrid Implant Enriched with Hyperstable Fibroblast Growth Factor 2

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

An experimental animal study was designed to investigate the intervertebral fusion efficiency and safety of a bioresorbable ceramic/biopolymer hybrid implant enriched with FGF2-STAB(R) in comparison with a tricortical bone autograft used as a gold standard. Twenty-four experimental pigs underwent L2/3 discectomy with implantation of either the tricortical iliac crest bone autograft or the bioresorbable hybrid implant (BHI) followed by lateral intervertebral fixation. The quality of spinal fusion was assessed by micro-computed tomography (micro-CT), biomechanical testing, and histological examination at both 8 and 16 weeks after the surgery.

Klíčová slova

micro-CT, biomechanics, histology, animal model, lumbar spinal fusion, tissue engineering, autograft, ceramic, collagen, FGF2

Autoři

KRTIČKA, M.; PLÁNKA, L.; VOJTOVÁ, L.; NEKUDA, V.; ŠŤASTNÝ, P.; SEDLÁČEK, R.; BŘÍNEK, A.; KAVKOVÁ, M.; GÖPFERT, E.; HEDVIČÁKOVÁ, V.; RAMPICHOVÁ, M.; KŘEN, L.; LIŠKOVÁ, K.; IRA, D.; DORAZILOVÁ, J.; SUCHÝ, T.; ZIKMUND, T.; KAISER, J.; STARÝ, D.; FALDYNA, M.; TRUNEC, M.

Vydáno

25. 6. 2021

Nakladatel

MDPI

ISSN

2227-9059

Periodikum

Biomedicines

Ročník

9

Číslo

7

Stát

Švýcarská konfederace

Strany od

733

Strany do

758

Strany počet

25

URL

https://www.mdpi.com/2227-9059/9/7/733

Plný text v Digitální knihovně

http://hdl.handle.net/11012/202260

BibTex

@article{BUT172841,
  author="Milan {Krtička} and Ladislav {Plánka} and Lucy {Vojtová} and Vladimír {Nekuda} and Přemysl {Šťastný} and Radek {Sedláček} and Adam {Břínek} and Michaela {Kavková} and Eduard {Göpfert} and Věra {Hedvičáková} and Michaela {Rampichová} and Leoš {Křen} and Květoslava {Lišková} and Daniel {Ira} and Jana {Matulová} and Tomáš {Suchý} and Tomáš {Zikmund} and Jozef {Kaiser} and David {Starý} and Martin {Faldyna} and Martin {Trunec}",
  title="Lumbar Interbody Fusion Conducted on a Porcine Model with a Bioresorbable Ceramic/Biopolymer Hybrid Implant Enriched with Hyperstable Fibroblast Growth Factor 2",
  journal="Biomedicines",
  year="2021",
  volume="9",
  number="7",
  pages="733--758",
  doi="10.3390/biomedicines9070733",
  issn="2227-9059",
  url="https://www.mdpi.com/2227-9059/9/7/733"
}