Production of P(3HB-co-4HB) copolymer by new thermophilic isolate Aneurinibacillus sp. H1 in batch, repated-batch and fed-batch cultivation modes of cultivation

abstrakt

angličtina

Extremophilic organisms are promising producers of biotechnological productions, because thanks to living in extreme conditions the biotechnological process is not so demanding on sterility and the biotechnological price of production is cheaper. Polyhydroxyalkanoates are microbial polyesters that are fully degradable and biocompatible. They are also a good alternative to petroleum polymers. Using our original protocol to isolate thermophilic PHA producers from natural source, we isolated the bacteria, which, was designated as Aneurinibacillus sp. H1. This bacterium is capable of producing poly(3-hydroxybutyrate) (P3HB) on glycerol (even on waste glycerol) , and, furthermore, when supplemented with proper precursors, it is able to produce copolymer poly(3-hydroxybutyrate-co-3-hydroxyvalerate) or poly(3-hydroxybutyrate-co-4-hydroxybutyrate) or even terpolymer poly(3-hydroxybutyrate-co-4-hydroxybutyrate-co-3-hydroxyvalerate) with very high 4-hydroxybutyrate and 3-hydroxyvalerate fractions.

Polyhydroxyalkanoates, extremophilic, thermophilic, Aneurinibacillus

PERNICOVÁ, I.; KOUŘILOVÁ, X.; NOVÁČKOVÁ, I.; SEDLÁČEK, P.; OBRUČA, S.

25. 2. 2021

1314-3530

Biotechnology and Biotechnological Equipment

1

35

Spojené království Velké Británie a Severního Irska

1

1

1