Detail publikace

Collagen-phosphate porous scaffolds for novel bone tissue engineering concept

BRTNÍKOVÁ, J. PAVLIŇÁKOVÁ, V. ŠŤASTNÝ, P. TRUNEC, M. POLÁČEK, P. BLAHNOVÁ, V. FILOVA, E. VOJTOVÁ, L.

Originální název

Typ

abstrakt

Jazyk

angličtina

Originální abstrakt

In this work, the bovine collagen type I was combined with calcium phosphates differing in solubility and resorbability. The effect of bioceramics solubility and particle sizes on scaffolds morphology, biomechanics, physical and biological properties was observed. Addition of bioceramic particles changed morphology of the samples resulting in decreasing the pore size, while the porosity becomes nearly the same in all tested samples. The biomechanical properties of the samples were tested in both dry and hydrated state. In dry state, collagen scaffolds reached the highest compressive strength, in contrary to the hydrated state, where samples containing bioceramic particles were stiffer but the strength values were one order lower comparing to samples in dry state. During in-vitro experiments, none of samples was found to be cytotoxic.

Klíčová slova

collagen scaffold, hydroxyapatite, α- and β-tricalcium phosphate

Autoři

BRTNÍKOVÁ, J.; PAVLIŇÁKOVÁ, V.; ŠŤASTNÝ, P.; TRUNEC, M.; POLÁČEK, P.; BLAHNOVÁ, V.; FILOVA, E.; VOJTOVÁ, L.

Vydáno

3. 12. 2018

Nakladatel

iMedPub LTD

Místo

London, UK

ISSN

2394-9988

Periodikum

International Journal of Applied Science-Research and Review

Ročník

Číslo

Stát

Spojené království Velké Británie a Severního Irska

Strany od

Strany do

Strany počet

BibTex

@misc{BUT159489,
  author="Jana {Brtníková} and Veronika {Pavliňáková} and Přemysl {Šťastný} and Martin {Trunec} and Petr {Poláček} and Veronika {Blahnová} and Eva {Filova} and Lucy {Vojtová}",
  title="Collagen-phosphate porous scaffolds for novel bone tissue engineering concept",
  year="2018",
  journal="International Journal of Applied Science-Research and Review",
  volume="C2",
  number="5",
  pages="29--29",
  publisher="iMedPub LTD",
  address="London, UK",
  doi="10.21767/2394-9988-C2-006",
  issn="2394-9988",
  note="abstract"
}