Detail publikace

Generation of humanized bone-marrow-like niche in immunodeficient mice

ČULEN, M. KOSAŘOVÁ, Z. SOKOL, F. CHOVANCOVÁ, J. DVOŘÁKOVÁ, D. VOJTOVÁ, L. RÁČIL, Z.

Originální název

Typ

konferenční sborník (ne článek)

Jazyk

angličtina

Originální abstrakt

Imunodeficient mice represent a standard in vivo model for study of different types of human leukemias. Not all leukemic cells, however, do engraft/proliferate after xenotransplantation to mice, which is supposedly caused by inter-species differences. This problem can be resolved by introducing a humanized microenvironment into the animal recipients, via sub-cutaneous implantation of a suitable biomaterial and human mesenchymal stromal cells (MSC).

Klíčová slova

bone-marrow, immunodeficient mice, collagen scaffold, mesenchymal stomal cells

Autoři

ČULEN, M.; KOSAŘOVÁ, Z.; SOKOL, F.; CHOVANCOVÁ, J.; DVOŘÁKOVÁ, D.; VOJTOVÁ, L.; RÁČIL, Z.

Vydáno

20. 4. 2017

Nakladatel

Symma s.r.o.

Místo

Brno

Strany od

Strany do

Strany počet

BibTex

@proceedings{BUT145082,
  editor="Martin {Čulen} and Zdeňka {Kosařová} and Filip {Sokol} and Jana {Chovancová} and Dana {Dvořáková} and Lucy {Vojtová} and Zdeněk {Ráčil}",
  title="Generation of humanized bone-marrow-like niche in immunodeficient mice",
  year="2017",
  pages="41--41",
  publisher="Symma s.r.o.",
  address="Brno"
}