Detail publikace

Bioactive Zirconia-Based Porous Scaffolds For Potential Bone Graft Applications

NOVOTNÁ, L. CIHLÁŘ, J.

Originální název

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

Alumina toughened zirconia (ATZ) / calcium phosphate (Ca-P) composite scaffolds were fabricated via polymer replica technique, the technique that best mimics the macrostructure of trabecular bone. Strong inert core based on ATZ was composed of microsized zirconia powder bonded by colloidal solution of boehmite. Sintered scaffolds were coated by suspension composed of hydroxyapatite / tricalcium phosphate powders and PVB binder. Scaffolds exhibited well-interconnected structure with pore sizes ranging from 300 to 1200 µm. Different porosity (50-98%) was achieved by repeating the replication process 1-6 times. The Ca-P coating with a thickness of about 50 µm was firmly adhered to the ATZ core. Neither of tested materials was cytotoxic. The apatite formation, appeared on the surface of coated scaffolds after immersion in simulated body fluid (SBF) indicated a good bioactivity of the ATZ/Ca-P composite.

Klíčová slova

zirconia, Ca-phosphates, scaffold, template method

Autoři

NOVOTNÁ, L.; CIHLÁŘ, J.

Rok RIV

2015

Vydáno

28. 5. 2015

ISBN

978-80-214-5146-9

Kniha

Multi-scale Design of Advanced Materials - Conference Proceedings

Strany od

Strany do

Strany počet

BibTex

@inproceedings{BUT114788,
  author="Lenka {Novotná} and Jaroslav {Cihlář}",
  title="Bioactive Zirconia-Based Porous Scaffolds For Potential Bone Graft Applications
",
  booktitle="Multi-scale Design of Advanced Materials - Conference Proceedings",
  year="2015",
  pages="93--99",
  isbn="978-80-214-5146-9"
}