Detail projektu

Soluble materials for dried blood spot self-sampling and automated analysis

Období řešení: 01.02.2021 — 31.01.2022

Zdroje financování

Evropská unie - Interní grantová soutěž

- plně financující (2021-02-01 - 2022-01-31)

O projektu

The project aims at the development of novel soluble materials for dried blood spot (DBS) self-sampling, their automated pretreatment and analysis. Simple DBS sampling, full solubility of the sampling materials and compatibility of sampling devices with commercial capillary electrophoresis will facilitate a fully autonomous process for biomedical assays. This will include DBS elution and clean-up, analyte extraction and quantitative analysis and will be exemplified by the determination of selected drugs as bio-medically relevant analytes.

Popis anglicky
The aim of the project is to create a competition for student research grants and its pilot verification. The creation of a new competition will contribute to the development of cross-sectional skills of doctoral students, and thus acquire competencies for work in science and research in the future and increase their success in submitting scientific projects to national and international competitions.

Označení

FCH-K-21-7023

Originální jazyk

čeština

Řešitelé

Ryšavá Lenka, Ing., Ph.D. - hlavní řešitel
Matulová Jana, Ing. - spoluřešitel

Útvary

Fakulta chemická
- příjemce (01.02.2021 - 31.01.2022)

Výsledky

RYŠAVÁ, L.; DORAZILOVÁ, J.; DVOŘÁK, M.; VOJTOVÁ, L.; SEDLÁČEK, P.; KUBÁŇ, P. Development of soluble materials for dried blood spot sampling and analysis. Department of Analytical Chemistry, Faculty of Chemistry, Jagiellonian University in Krakow, Krakow 2021, 2021. p. 131-132.
Detail

KUBÁŇ, P.; RYŠAVÁ, L.; DVOŘÁK, M. Capillary electrophoresis for the automated extraction and analysis of dried blood spots in clinical analysis. 2021.
Detail

DORAZILOVÁ, J.; RYŠAVÁ, L.; SEDLÁČEK, P.; DVOŘÁK, M.; VOJTOVÁ, L.; KUBÁŇ, P. Vývoj 3D rozpustných polymerních sorbčních pěn specificky interagujících s krví pro klinické aplikace. Praha: České vysoké učení technické v Praze, 2021. s. 33-34.
Detail

RYŠAVÁ, L.; DVOŘÁK, M.; VOJTOVÁ, L.; DORAZILOVÁ, J.; SEDLÁČEK, P.; KUBÁŇ, P. Fully soluble polymeric foams for in-vial dried blood spot collection and analysis of acidic drugs by capillary electrophoresis. ANALYTICA CHIMICA ACTA, 2023, vol. 1241, no. 340793, ISSN: 0003-2670.
Detail

DVOŘÁK, M.; RYŠAVÁ, L.; MIRO, M.; KUBÁŇ, P. DIRECT ANALYSIS OF DRIED BLOOD SPOTS BY AUTOMATED SEQUENTIAL INJECTION-CAPILLARY ELECTROPHORESIS. 2021.
Detail

KUBÁŇ, P.; RYŠAVÁ, L.; DVOŘÁK, M. Capillary Electrophoresis for the Automated Extraction and Analysis of Dried Blood Spots in Clinical Analysis. 2021. p. 55-55.
Detail

BLANKA, M.; DVOŘÁK, M.; RYŠAVÁ, L.; GEBAUER, P.; MALÁ, Z.; KUBÁŇ, P. At-line coupling of hollow fiber liquid-phase microextraction to capillary electrophoresis for trace determination of acidic drugs in complex samples. Talanta, 2022, vol. 3, no. 2, p. 238-248. ISSN: 0039-9140.
Detail