The course focuses on the application of basic theoretical knowledge of physical chemistry to the biological systems. It represents a borderline course between physics, chemistry and biology, which allow obtaining molecular and structural perspective on biologically important and medically important pehnomena. Attention is drawn to an impact of the basic theoretical knowledge into analytical (advanced methods of study and interpretation of the structure and function of biopolymers) and application fields. Special topics: biothermodynamics: energetics of biological processes, Gibbs energy and its role in biological processes. Kinetics of biological processes, enzyme reactions, denaturation and renaturation. Non-covalent interactions in biological systems; 3D structure of biopolymers. Biomembranes. Water and hydratation. Biological polyelectrolytes.